Making a Point: Picoscale Stability in a Room-Temperature AFM


Forget dancing angels, a research team from the National Institute of Standards and Technology (NIST) and the University of Colorado (CU) has shown how to detect and monitor the tiny amount of light reflected directly off the needle point of an atomic force microscope probe, and in so doing has demonstrated a 100-fold improvement in the stability of the instrument’s measurements under ambient conditions. Their recently reported work* potentially affects a broad range of research from nanomanufacturing to biology, where sensitive, atomic-scale measurements must be made at room temperature in liquids.

Atomic force microscopes (AFMs) are one of the workhorse tools of nanotechnology. AFMs have a sharp, pointed probe fixed to one end of a diving-board-like cantilever. As the probe is scanned across a sample, atomic-scale forces tug at the probe tip, deflecting the cantilever. By reflecting a laser beam from the top of the cantilever, researchers can sense changes in the force and build up a nanoscale topographic image of the sample. The instruments are terrifically versatile—in various configurations they can image electrostatic forces, chemical bonds, magnetic forces and other atomic-scale interactions.